Reaction Details Report a problem with these data
Target
P2X purinoceptor 3
Ligand
BDBM118156
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
>10000±n/a nM
Citation
 Wei, Z; Kincaid, J; Kelly, MG; O'Mahony, DJ; Kaub, C Pyrid-2yl fused heterocyclic compounds, and compositions and uses thereof US Patent  US8653091 Publication Date 2/18/2014 
Target
Name:
P2X purinoceptor 3
Synonyms:
ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa
Type:
Protein
Mol. Mass.:
44292.02
Organism:
Homo sapiens (Human)
Description:
P56373
Residue:
397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
  
Inhibitor
Name:
BDBM118156
Synonyms:
US8653091, 51
Type:
Small organic molecule
Emp. Form.:
C20H18ClF3N6
Mol. Mass.:
434.845
SMILES:
C[C@H](Nc1ncnc2CCN(Cc12)c1ccc(Cl)cn1)c1ccc(nc1)C(F)(F)F |r|
Structure:
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