Reaction Details Report a problem with these data
Target
P2X purinoceptor 3
Ligand
BDBM118169
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
17±n/a nM
Citation
 Wei, Z; Kincaid, J; Kelly, MG; O'Mahony, DJ; Kaub, C Pyrid-2yl fused heterocyclic compounds, and compositions and uses thereof US Patent  US8653091 Publication Date 2/18/2014 
Target
Name:
P2X purinoceptor 3
Synonyms:
ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa
Type:
Protein
Mol. Mass.:
44292.02
Organism:
Homo sapiens (Human)
Description:
P56373
Residue:
397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
  
Inhibitor
Name:
BDBM118169
Synonyms:
US8653091, 64
Type:
Small organic molecule
Emp. Form.:
C20H23N7
Mol. Mass.:
361.4435
SMILES:
C[C@@H](Nc1ncnc2CCN(Cc12)c1ccc(C)cn1)c1cnc(C)nc1 |r|
Structure:
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