Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM136362
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±n/a
Ki
0.16±n/a nM
Comments
extracted
Citation
 Andersson, J; Gyback, H; Johansson, A; Linde, CE; Malmstrom, J; Nordvall, G; Weigelt, T; Terp, G 2-carboxamide-7-piperazinyl-benzofuran derivatives US Patent  US8859534 Publication Date 10/14/2014 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-hydroxytryptamine receptor 1A (5HT1A)
Type:
Protein
Mol. Mass.:
46351.20
Organism:
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Description:
G3I1B6
Residue:
422
Sequence:
MDIFSLGQGNNTTSSQEPFGTGGNVTGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGASTSLSTSSAPPPKKSLNGQPGNGDWRRSAENRAVGAPCANGAVRQGDDEATLEVIEVHRVGNSKDHLPLPSESGATSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR
  
Inhibitor
Name:
BDBM136362
Synonyms:
US8859534, 48
Type:
Small organic molecule
Emp. Form.:
C23H28N4O3
Mol. Mass.:
408.4934
SMILES:
COc1cccnc1CCN1CCN(CC1)c1cccc2cc(oc12)C(=O)N(C)C
Structure:
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