Target
Alpha-synuclein
Ligand
BDBM170546
Substrate
n/a
Meas. Tech.
Competitive Binding Assay
pH
7.4±n/a
Ki
89±n/a nM
Comments
extracted
Citation
 Luke, EAYadon, MCCummings, JHudson, FMLake, THu, QCam, JSnow, AD Compounds for the treatment of neurodegenerative diseases US Patent  US9085549 Publication Date 7/21/2015 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM170546
Synonyms:
US9085549, 57 | US9085549, 64
Type:
Small organic molecule
Emp. Form.:
C14H10N2O4S
Mol. Mass.:
302.305
SMILES:
Oc1ccc(cc1O)-c1nsc(n1)-c1ccc(O)c(O)c1
Structure:
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