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Reaction Details
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TargetAdenosine receptor A3
LigandBDBM191057
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
pH7.5±n/a
Temperature298.15±n/a K
Ki 8.9±1.9 nM
Commentsextracted
Citation Jacobson, KATosh, DK Adenosine receptor agonists, partial agonists, and antagonists US Patent US9181253 Publication Date 11/10/2015
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A3
Name:Adenosine receptor A3 (A3)
Synonyms:Adenosine receptor A3
Type:Protein
Mol. Mass.:36197.32
Organism:Homo sapiens (Human)
Description:n/a
Residue:318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSLINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM191057
NameBDBM191057
Synonyms:US9181253, 119
TypeSmall organic molecule
Emp. Form.C15H18ClN5O2
Mol. Mass.335.789
SMILESO[C@H]1C[C@]2(C[C@H]2[C@H]1O)n1cnc2c(NCC3CC3)nc(Cl)nc12 |r|
Structure
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n/a