Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAdenosine receptor A3
LigandBDBM191062
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
pH7.5±n/a
Temperature298.15±n/a K
Ki 15.2±3 nM
Commentsextracted
Citation Jacobson, KATosh, DK Adenosine receptor agonists, partial agonists, and antagonists US Patent US9181253 Publication Date 11/10/2015
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A3
Name:Adenosine receptor A3 (A3)
Synonyms:Adenosine receptor A3
Type:Protein
Mol. Mass.:36197.32
Organism:Homo sapiens (Human)
Description:n/a
Residue:318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSLINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM191062
NameBDBM191062
Synonyms:US9181253, 124
TypeSmall organic molecule
Emp. Form.C20H22ClN5O3
Mol. Mass.415.873
SMILESCCOc1ccccc1CNc1nc(Cl)nc2n(cnc12)[C@]12C[C@H]1[C@@H](O)[C@@H](O)C2 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a