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TargetMacrophage colony-stimulating factor 1 receptor (CSF1R) or (c-fms)
LigandBDBM50443132
Substrate/Competitorn/a
Meas. Tech.Fluorescence Polarization Competition Immunoassay
pH7.5±n/a
IC50 1.43±n/a nM
Commentsextracted
Citation Illig, CRBallentine, SKChen, JDesjarlais, RLMeegalla, SKWall, MWilson, K Inhibitors of c-fms kinase US Patent US9221797 Publication Date 12/29/2015
More Info.:Get all data from this article,  Assay Method
 
Macrophage colony-stimulating factor 1 receptor (CSF1R) or (c-fms)
Name:Macrophage colony-stimulating factor 1 receptor (CSF1R) or (c-fms)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:1619.64
Organism:Homo sapiens (Human)
Description:CSF-1R phosphorylation of tyrosine on a synthetic CSF-1R 555-568 peptide (SYEGNSYTFIDPTQ)
Residue:14
Sequence:
SYEGNSYTFIDPTQ
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BDBM50443132
NameBDBM50443132
Synonyms:CHEMBL3086175 | US9221797, 42
TypeSmall organic molecule
Emp. Form.C23H27N5O2
Mol. Mass.405.4928
SMILESO=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N |t:19|
Structure
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