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Target
RAC-alpha serine/threonine-protein kinase [1-123]
Ligand
BDBM50304368
Substrate
n/a
Meas. Tech.
Cellular Assay
IC50
15000±n/a nM
Citation
 Mahadevan, D; Meuillet, EJ; Mash, Jr., EA; Gokhale, VM; Powis, G; Zhang, S Small molecule inhibitors of the pleckstrin homology domain and methods for using same US Patent  US9320734 Publication Date 4/26/2016 
Target
Name:
RAC-alpha serine/threonine-protein kinase [1-123]
Synonyms:
AKT1 | AKT1_HUMAN | PKB | RAC | RAC-alpha serine/threonine-protein kinase (Akt)
Type:
Enzyme
Mol. Mass.:
14664.42
Organism:
Homo sapiens (Human)
Description:
PLECKSTRIN HOMOLOGY DOMAIN RESIDUES 1-123 (PH Domain)
Residue:
123
Sequence:
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSG
  
Inhibitor
Name:
BDBM50304368
Synonyms:
CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfamoyl)phenyl)decanamide | US9320734, 101
Type:
Small organic molecule
Emp. Form.:
C18H26N4O3S2
Mol. Mass.:
410.554
SMILES:
CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Structure:
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