Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Serine/threonine-protein kinase Chk1 [2-280]
Ligand
BDBM91965
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
3590±n/a nM
More Info.:
Target
Name:
Serine/threonine-protein kinase Chk1 [2-280]
Synonyms:
CHEK1 | CHK1 | CHK1_HUMAN | CHK1_Kinase
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
O14757[2-280]
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
Inhibitor
Name:
BDBM91965
Synonyms:
Chk1_96
Type:
n/a
Emp. Form.:
C26H25N3O4
Mol. Mass.:
443.4944
SMILES:
COc1cc(ccc1C(=O)N1CCCC1CO)-c1ccc2c(Nc3ccccc3NC2=O)c1
Structure:
