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Target
Tyrosine-protein kinase SYK [355-635]
Ligand
BDBM225538
Substrate
n/a
Meas. Tech.
SYK assay_HTRF
IC50
1.58±n/a nM
Citation
 D3R, DD GSK SYK Kinase D3R 225:0 (2015) [PubMed] 
Target
Name:
Tyrosine-protein kinase SYK [355-635]
Synonyms:
KSYK_HUMAN | SYK | SYK Kinase
Type:
n/a
Mol. Mass.:
32610.83
Organism:
Homo sapiens (Human)
Description:
P43405[355-635]
Residue:
281
Sequence:
PEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
  
Inhibitor
Name:
BDBM225538
Synonyms:
GTC000242A
Type:
Small Organic Molecule
Emp. Form.:
C24H25FN8O
Mol. Mass.:
460.5067
SMILES:
CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F
Structure:
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