Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Ligand
BDBM92302
Substrate
n/a
Meas. Tech.
Photometric_Method1
Ki
15.7±n/a nM
Citation
 D3R, DD Abbott Urokinase D3R 227:0 (2015) [PubMed] 
Target
Name:
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Synonyms:
PLAU | UROK_HUMAN | Urokinase
Type:
n/a
Mol. Mass.:
27687.84
Organism:
Homo sapiens (Human)
Description:
P00749[179-424,C299A,N323Q]
Residue:
246
Sequence:
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK
  
Inhibitor
Name:
BDBM92302
Synonyms:
uPa_26
Type:
n/a
Emp. Form.:
C24H23BrN4O
Mol. Mass.:
463.37
SMILES:
CC(C)C1=NCCc2ccc(NC(=O)c3cc(Br)c4cc(ccc4c3)C(N)=N)cc12 |t:3|
Structure:
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