Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Ligand
BDBM92322
Substrate
n/a
Meas. Tech.
Photometric_Method1
Ki
1250±n/a nM
Citation
 D3R, DD Abbott Urokinase D3R 227:0 (2015) [PubMed] 
Target
Name:
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Synonyms:
PLAU | UROK_HUMAN | Urokinase
Type:
n/a
Mol. Mass.:
27687.84
Organism:
Homo sapiens (Human)
Description:
P00749[179-424,C299A,N323Q]
Residue:
246
Sequence:
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK
  
Inhibitor
Name:
BDBM92322
Synonyms:
uPa_44
Type:
n/a
Emp. Form.:
C29H28N4
Mol. Mass.:
432.5594
SMILES:
CN1CCc2ccc(cc2C1c1cccnc1)C1CC1c1ccc2cc(ccc2c1)C(N)=N
Structure:
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