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TargetGlucose-6-phosphate 1-dehydrogenase
LigandBDBM233194
Substrate/Competitorn/a
Meas. Tech.In Vitro Inhibition Assay
Ki 5.405e+5± 1.528e+5 nM
IC50 2.230e+6±n/a nM
Citation Akkemik, EBudak, HCiftci, M Effects of some drugs on human erythrocyte glucose 6-phosphate dehydrogenase: an in vitro study. J Enzyme Inhib Med Chem25:871-5 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glucose-6-phosphate 1-dehydrogenase
Name:Glucose-6-phosphate 1-dehydrogenase
Synonyms:Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:Enzyme
Mol. Mass.:59258.58
Organism:Homo sapiens (Human)
Description:P11413
Residue:515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM233194
NameBDBM233194
Synonyms:Methylprednisolone acetate
TypeSmall organic molecule
Emp. Form.C24H32O6
Mol. Mass.416.5073
SMILESC[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)COC(C)=O)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12 |c:26,t:30|
Structure
n/a