Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM85804
Substrate
n/a
Meas. Tech.
Functional Assay
Ki
12.9±3.4 nM
Citation
 Prather, PL; Prisinzano, TE; Fantegrossi, WE; Brents, LK; Moran, J; Radominska-Pandya, A; Vasiljevik, T Use of the aminoalkylindole JWH-073-M4 and related compounds as neutral CB1 receptor antagonists for the treatment of alcoholism, drug abuse, obesity, and obesity-related diseases US Patent  US9416103 Publication Date 8/16/2016 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1
Type:
Enzyme
Mol. Mass.:
52842.52
Organism:
Mus musculus (Mouse)
Description:
P47746
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM85804
Synonyms:
1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-073 | US9416103, JWH-073
Type:
Small organic molecule
Emp. Form.:
C23H21NO
Mol. Mass.:
327.4189
SMILES:
CCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Structure:
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