Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM259967
Substrate
n/a
Meas. Tech.
cAMP Assay
Temperature
310.15±n/a K
EC50
5.1±n/a nM
Comments
extracted
Citation
 Grether, U; Kimbara, A; Matthias, N; Fabienne, R; Stephan, R; Rogers-Evans, M; Schulz-Gasch, T Pyrazole compounds as CB2 agonists US Patent  US9512132 Publication Date 12/6/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM259967
Synonyms:
US9512132, 3
Type:
Small organic molecule
Emp. Form.:
C20H24ClN5O
Mol. Mass.:
385.89
SMILES:
CC(C)(C)c1nc(N2CC[C@H](O)C2)c2cnn(Cc3ccccc3Cl)c2n1 |r|
Structure:
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