Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM434831
Substrate
n/a
Meas. Tech.
Binding Assays
Ki
0.540±0.10 nM
Citation
 Jacobson, KA; Tosh, DK; Salvemini, D A3 adenosine receptor agonists US Patent  US10577368 Publication Date 3/3/2020 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM434831
Synonyms:
US10577368, Compound 113
Type:
Small organic molecule
Emp. Form.:
C14H17N9O3
Mol. Mass.:
359.3433
SMILES:
CNC(=O)[C@]12CC1[C@H]([C@H](O)C2O)n1cnc2c(NC)nc(N=[N+]=[N-])nc12 |r|
Structure:
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