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TargetStructural polyprotein
LigandBDBM476299
Substrate/Competitorn/a
Meas. Tech.CPE Assay
EC50>78000±n/a nM
Citation Painter, GRGuthrie, DBBluemling, GRNatchus, MR N4-hydroxycytidine and derivatives and anti-viral uses related thereto US Patent US10874683 Publication Date 12/29/2020
More Info.:Get all data from this article,  Assay Method
 
Structural polyprotein
Name:Structural polyprotein
Synonyms:p130
Type:Protein
Mol. Mass.:138165.86
Organism:CHIKV
Description:Q8JUX5
Residue:1248
Sequence:
MEFIPTQTFYNRRYQPRPWTPRPTIQVIRPRPRPQRQAGQLAQLISAVNKLTMRAVPQQK
PRRNRKNKKQKQKQQAPQNNTNQKKQPPKKKPAQKKKKPGRRERMCMKIENDCIFEVKHE
GKVTGYACLVGDKVMKPAHVKGTIDNADLAKLAFKRSSKYDLECAQIPVHMKSDASKFTH
EKPEGYYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGARTAL
SVVTWNKDIVTKITPEGAEEWSLAIPVMCLLANTTFPCSQPPCIPCCYEKEPEETLRMLE
DNVMRPGYYQLLQASLTCSPHRQRRSTKDNFNVYKATRPYLAHCPDCGEGHSCHSPVALE
RIRNEATDGTLKIQVSLQIGIGTDDSHDWTKLRYMDNHIPADAGRAGLFVRTSAPCTITG
TMGHFILARCPKGETLTVGFTDSRKISHSCTHPFHHDPPVIGREKFHSRPQHGKELPCST
YVQSNAATAEEIEVHMPPDTPDRTLLSQQSGNVKITVNGRTVRYKCNCGGSNEGLITTDK
VINNCKVDQCHAAVTNHKKWQYNSPLVPRNAELGDRKGKIHIPFPLANVTCMVPKARNPT
VTYGKNQVIMLLYPDHPTLLSYRSMGEEPNYQEEWVTHKKEVVLTVPTEGLEVTWGNNEP
YKYWPQLSANGTAHGHPHEIILYYYELYPTMTVVVVSVASFILLSMVGMAVGMCMCARRR
CITPYELTPGATVPFLLSLICCIRTAKAATYQEAAVYLWNEQQPLFWLQALIPLAALIVL
CNCLRLLPCCCKTLAFLAVMSIGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEM
ELLSVTLEPTLSLDYITCEYKTVIPSPYVKCCGTAECKDKNLPDYSCKVFTGVYPFMWGG
AYCFCDAENTQLSEAHVEKSESCKTEFASAYRAHTASASAKLRVLYQGNNITVTAYANGD
HAVTVKDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESK
DVYANTQLVLQRPAAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAMNC
AVGNMPISIDIPDAAFTRVVDAPSLTDMSCEVPACTHSSDFGGVAIIKYAVSKKGKCAVH
SMTNAVTIREAEIEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYP
ASHTTLGVQDISATAMSWVQKITGGVGLVVAVAALILIVVLCVSFSRH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM476299
NameBDBM476299
Synonyms:US10874683, Example 00106 | US10874683, Example 56.1 | US10874683, Example EIDD-01931-04 | US10874683, Example EIDD-02200-01 | US10874683, Example EIDD-02261-01 | US10874683, Example EIDD-02345-01 | US10874683, Example EIDD-02416-01
TypeSmall organic molecule
Emp. Form.C9H13N3O6
Mol. Mass.259.216
SMILESOC[C@H]1O[C@H](C(O)[C@H]1O)n1ccc(NO)nc1=O |r|
Structure
n/a