Reaction Details Report a problem with these data
Target
TSC22 domain family protein 3
Ligand
BDBM50354849
Substrate
n/a
Meas. Tech.
GILZ gene assays
IC50
0.150±n/a nM
Citation
 Garbaccio, RM; Kern, JC; Mulhearn, JJ; Brandish, PE Phosphonate linkers and their use to facilitate cellular retention of compounds US Patent  US10869929 Publication Date 12/22/2020 
Target
Name:
TSC22 domain family protein 3
Synonyms:
DSIP-immunoreactive peptide | DSIPI | Delta sleep-inducing peptide immunoreactor | GILZ | Glucocorticoid-induced leucine zipper protein | Protein DIP | T22D3_HUMAN | TSC-22-like protein | TSC-22-related protein | TSC-22R | TSC22D3 | hDIP
Type:
Protein
Mol. Mass.:
14799.51
Organism:
Human
Description:
Q99576
Residue:
134
Sequence:
MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEPAPESPQVPEAPGGSAV
  
Inhibitor
Name:
BDBM50354849
Synonyms:
CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Flonase | Flovent | Flovent diskus 100 | Flovent diskus 250 | Flovent diskus 50 | Flovent hfa | Fluticasone | US10869929, Compound FLUTICASONE PROPIONATE
Type:
Small organic molecule
Emp. Form.:
C25H31F3O5S
Mol. Mass.:
500.571
SMILES:
CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF |r,c:18,t:14|
Structure:
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