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Target
N-formyl peptide receptor 2
Ligand
BDBM497393
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
28.0±n/a nM
Citation
 Shirude, PS; Chattopadhyay, AK; Rachamreddy, C; Wurtz, NR; Kick, EK Piperidinone formyl peptide 2 receptor agonists US Patent  US11008301 Publication Date 5/18/2021 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM497393
Synonyms:
US11008301, Example 4
Type:
Small organic molecule
Emp. Form.:
C24H25F3N4O3
Mol. Mass.:
474.4755
SMILES:
FC(F)(F)c1ccc(NC(=O)N[C@@H]2CCCN(C2=O)c2ccc(cc2)N2CCCCC2=O)cc1 |r|
Structure:
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