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TargetStimulator of interferon genes protein [139-379,H232R]
LigandBDBM501193
Substrate/Competitorn/a
Meas. Tech.STING SPA Binding Assay
IC50 54500±n/a nM
Citation Emanuel, SRichter, MConnolly, PJEdwards, JPWang, GThatikonda, SKBeigelman, LZhong, MBignan, G Cyclic dinucleotides as sting agonists US Patent US11021511 Publication Date 6/1/2021
More Info.:Get all data from this article,  Assay Method
 
Stimulator of interferon genes protein [139-379,H232R]
Name:Stimulator of interferon genes protein [139-379,H232R]
Synonyms:Stimulator of interferon genes protein (aa 139-379 H232R)
Type:Enzyme Catalytic Domain
Mol. Mass.:27090.78
Organism:Homo sapiens (Human)
Description:n/a
Residue:241
Sequence:
LAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRL
YILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDRAGIKDRVYSNSIYELLENGQRAGTCV
LEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPA
DDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDF
S
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM501193
NameBDBM501193
Synonyms:US11021511, Compound 1
TypeSmall organic molecule
Emp. Form.C21H26N10O13P2
Mol. Mass.688.4379
SMILESCC1(O)C(OC2COP(O)(=O)OC3C(O)C(COP(O)(=O)OC12)OC3n1cnc2c1nc(N)[nH]c2=O)n1cnc2c(N)ncnc12
Structure
n/a