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TargetStimulator of interferon genes protein (aa 139-379 H232R)
LigandBDBM501361
Substrate/Competitorn/a
Meas. Tech.STING Human Cell Reporter Assay
EC50 210±n/a nM
Citation Emanuel, SRichter, MConnolly, PJEdwards, JPWang, GThatikonda, SKBeigelman, LZhong, MBignan, G Cyclic dinucleotides as sting agonists US Patent US11021511 Publication Date 6/1/2021
More Info.:Get all data from this article,  Assay Method
 
Stimulator of interferon genes protein (aa 139-379 H232R)
Name:Stimulator of interferon genes protein (aa 139-379 H232R)
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:27090.78
Organism:Homo sapiens (Human)
Description:n/a
Residue:241
Sequence:
LAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRL
YILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDRAGIKDRVYSNSIYELLENGQRAGTCV
LEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPA
DDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDF
S
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  Blast E-value cutoff:
BDBM501361
NameBDBM501361
Synonyms:US11021511, Compound 5
TypeSmall organic molecule
Emp. Form.C21H25FN10O12P2
Mol. Mass.690.4289
SMILESNc1nc2n(cnc2c(=O)[nH]1)C1OC2COP(O)(=O)OC3C(COP(O)(=O)OC1C2CO)OC(C3F)n1cnc2c(N)ncnc12
Structure
n/a