| Reaction Details |
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 | Report a problem with these data |
| Target | Stimulator of interferon genes protein [138-378] |
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| Ligand | BDBM501361 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | STING SPA Binding Assay |
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| IC50 | 16.0±n/a nM |
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| Citation |  Emanuel, S; Richter, M; Connolly, PJ; Edwards, JP; Wang, G; Thatikonda, SK; Beigelman, L; Zhong, M; Bignan, G Cyclic dinucleotides as sting agonists US Patent US11021511 Publication Date 6/1/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Stimulator of interferon genes protein [138-378] |
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| Name: | Stimulator of interferon genes protein [138-378] |
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| Synonyms: | Stimulator of interferon genes protein (aa 138-378) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27213.36 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 241 |
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| Sequence: | LTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRL
YILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCI
LEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPT
DGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPSVLSQEPRLLISGMDQPLPLRTDL
I
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| BDBM501361 |
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| Name | BDBM501361 |
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| Synonyms: | US11021511, Compound 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25FN10O12P2 |
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| Mol. Mass. | 690.4289 |
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| SMILES | Nc1nc2n(cnc2c(=O)[nH]1)C1OC2COP(O)(=O)OC3C(COP(O)(=O)OC1C2CO)OC(C3F)n1cnc2c(N)ncnc12 |
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| Structure |  |
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| n/a |
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