Reaction Details Report a problem with these data
Target
Bromodomain-containing protein 2 [74-94]
Ligand
BDBM50452553
Substrate
n/a
Meas. Tech.
Isothermal Titration Calorimetry Analysis of Binding to Brd2-BD1 and Brd2-BD2
Kd
131±n/a nM
Citation
 Guy, RK; Slavish, PJ; Shadrick, WR; Young, BM; Boyd, VA; Bharatham, N; Price, JE; Shelat, A Tetrahydroquinoline-based bromodomain inhibitors US Patent  US11028051 Publication Date 6/8/2021 
Target
Name:
Bromodomain-containing protein 2 [74-94]
Synonyms:
BRD2 | BRD2-BD1 | BRD2_HUMAN | Bromodomain-containing protein 2 (aa 74-94) | KIAA9001 | RING3
Type:
n/a
Mol. Mass.:
2626.15
Organism:
Homo sapiens (Human)
Description:
P25440[74-94]
Residue:
21
Sequence:
RVTNQLQYLHKVVMKALWKHQ
  
Inhibitor
Name:
BDBM50452553
Synonyms:
CHEMBL4202664 | US11028051, Cmpd 54
Type:
Small organic molecule
Emp. Form.:
C20H25N3O3
Mol. Mass.:
355.4308
SMILES:
CC(C)OC(=O)N[C@@H]1C[C@H](C)N(C(C)=O)c2ccc(cc12)-c1ccc[nH]1 |r|
Structure:
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