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Target
FMR1 autosomal homolog 1
Ligand
BDBM504304
Substrate
n/a
Meas. Tech.
AlphaScreen Assay
EC50
730±10 nM
Citation
 Pellicciari, R; Gioiello, A Farnesoid X receptor modulators US Patent  US11034717 Publication Date 6/15/2021 
Target
Name:
FMR1 autosomal homolog 1
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
69744.00
Organism:
Dog
Description:
A0A8I3PAF1
Residue:
621
Sequence:
MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRESRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDEISKLQRTPGEEKINTLKEENTQEAAVLNGVS
  
Inhibitor
Name:
BDBM504304
Synonyms:
3α,7α,11β-rihydroxy-6α-ethyl-5β-cholan-24-O-sulphate, sodium salt | US11034717, Compound 5
Type:
Small organic molecule
Emp. Form.:
C26H45NaO7S
Mol. Mass.:
524.686
SMILES:
CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCCOS(=O)(=O)O[Na])[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r|
Structure:
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