Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetFMR1 autosomal homolog 1
LigandBDBM504311
Substrate/Competitorn/a
Meas. Tech.AlphaScreen Assay
EC50 700±10 nM
Citation Pellicciari, R; Gioiello, A Farnesoid X receptor modulators US Patent US11034717 Publication Date 6/15/2021
More Info.:Get all data from this article,  Assay Method
 
FMR1 autosomal homolog 1
Name:FMR1 autosomal homolog 1
Synonyms:n/a
Type:Protein
Mol. Mass.:69744.00
Organism:Dog
Description:A0A8I3PAF1
Residue:621
Sequence:
MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEIS
EGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKT
VKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKR
VNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSN
IQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN
GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKE
VEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELS
DWSLAGEDDRESRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLL
DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY
ISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDEISKLQRTPGE
EKINTLKEENTQEAAVLNGVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM504311
NameBDBM504311
Synonyms:3α,7α,11β-trihydroxy-6α-ethyl-23-(1,2,4-oxadiazol-5-oxo-3-yl)-23-nor-5β-cholane | US11034717, Compound 7
TypeSmall organic molecule
Emp. Form.C27H44N2O5
Mol. Mass.476.6487
SMILESCC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r|
Structure
n/a