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Target
Somatostatin receptor type 4
Ligand
BDBM506429
Substrate
n/a
Meas. Tech.
SSTR4 I-125 Somatostatin Competition Binding Assay
IC50
39.8±n/a nM
Citation
 Cheruvallath, Z; Green, J; Johnson, B; Schleicher, K; Sun, H; Tang, M Piperidinyl-3-(aryloxy)propanamides and propanoates US Patent  US11045457 Publication Date 6/29/2021 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM506429
Synonyms:
US11045457, Example 29
Type:
Small organic molecule
Emp. Form.:
C21H28F3N5O3
Mol. Mass.:
455.4739
SMILES:
CN1C[C@@H](NC(=O)C(C)(C)COc2ncccc2OC(F)(F)F)[C@@H](C1)c1cn(C)nc1C |r|
Structure:
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