| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
|---|
| Ligand | BDBM506619 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | S1P1 Binding Assay |
|---|
| EC50 | 14393±n/a nM |
|---|
| Citation |  Dyckman, AJ; Li, L; Gilmore, JL Alkylphenyl compounds US Patent US11046646 Publication Date 6/29/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 1 |
|---|
| Name: | Sphingosine 1-phosphate receptor 1 |
|---|
| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42836.02 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21453 |
|---|
| Residue: | 382 |
|---|
| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
|
|
|
|---|
| BDBM506619 |
|---|
| Name | BDBM506619 |
|---|
| Synonyms: | US11046646, Example 15 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H35N2O5P |
|---|
| Mol. Mass. | 426.4868 |
|---|
| SMILES | CCCCCCCCc1cc(C)c(N2CCC(N)(COP(O)(O)=O)C2=O)c(C)c1 |
|---|
| Structure |  |
|---|
| n/a |
|---|
Search and Browse
