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Target
D(2) dopamine receptor
Ligand
BDBM506804
Substrate
n/a
Meas. Tech.
D2 binding assay
Ki
152±n/a nM
Citation
 Duggan, ME; Edgar, DM Piperazine substituted azapine derivatives and uses thereof US Patent  US11046651 Publication Date 6/29/2021 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM506804
Synonyms:
-(4-(2,7-dimethyldibenzo[b,f][1,4]oxazepin-11-yl)piperazin-1-yl)-2,2-dimethylpropanoic acid | US11046651, Compound A-3
Type:
Small organic molecule
Emp. Form.:
C25H30N2O3
Mol. Mass.:
406.5173
SMILES:
Cc1ccc2N=C(C3CCN(CC(C)(C)C(O)=O)CC3)c3cc(C)ccc3Oc2c1 |t:5|
Structure:
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