| Assay Method Information | |
| | FXR Transient Transfection Assay |
| Description: | The cell-based assay measures the ligand-mediated luminescense resulting from FXR-induced transcription of a luciferase reporter. FXR and the luciferase reporter genes are transfected into African green monkey CV-1 kidney cells, then treated with test compound. The EC50 values are the mean of at least two assays. |
| Affinity data for this assay | |
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