Details for Substrate
Dual specificity mitogen-activated protein kinase kinase 1 without Explicit Binding Affinity Data |
Binding Enzyme 1: | Serine/threonine-protein kinase B-raf [410-766,V600E] |
Binding Enzyme 2: | RAF proto-oncogene serine/threonine-protein kinase [305-648] |
Binding Enzyme 3: | Serine/threonine-protein kinase B-raf [409-765] |
Synonyms: |
Dual specificity mitogen-activated protein kinase (MEK)
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Dual specificity mitogen-activated protein kinase kinase 1 (MEK)
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Dual specificity mitogen-activated protein kinase kinase 1 (MEK1)
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Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase
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Dual specificity mitogen-activated protein kinase kinase MEK1/2
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ERK activator kinase 1
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MAP kinase kinase 1
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MAP2K1
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MAPK/ERK kinase 1
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MAPK/ERK kinase 1 (MEK1)
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MEK-1
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MEK1
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MP2K1_HUMAN
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Mitogen-activated protein kinase 1 (MEK1)
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PRKMK1
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VHL-MAP2K1/MAP2K2
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Type: | Other Protein Type |
Topology: | Linear |
Mol. Mass.: | 43439.03 Dalton |
Organism: | Homo sapiens (Human) |
Description: | Full-length human MEK-1 was generated by PCR and purified as a fusion protein from Escherichia coli lysates. |
Residue: | 393 |
Sequence: | MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV |
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