BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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31 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2.EBI
Universit£
Pachymodulin, a new functional formyl peptide receptor 2 peptidic ligand isolated from frog skin has Janus-like immunomodulatory capacities.EBI
Sorbonne University
Development of potent antagonists for formyl peptide receptor 1 based on Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH.EBI
Saga University
Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2.EBI
Syntrix Biosystems
Lead optimisation of pyrazoles as novel FPR1 antagonists.EBI
Astrazeneca
Discovery of pyrazoles as novel FPR1 antagonists.EBI
Astrazeneca
Discovery of small molecule human FPR1 receptor antagonists.EBI
Astrazeneca
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: new potent inhibitors of fMLP-induced neutrophil chemotaxis.EBI
Universit£
Cyclosporins: structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor.EBI
Strasbourg 1 University
6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors.EBI
Universita Degli Studi Di Firenze
Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.EBI
Queen Mary University Of London
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.EBI
Kyorin Pharmaceutical
Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists.EBI
Monash University
Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity.EBI
University Of Florida
N-terminus urea-substituted chemotactic peptides: new potent agonists and antagonists toward the neutrophil fMLF receptor.EBI
Johnson Matthey Biomedical Research
Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation.EBI
Universit£
 
NAD+-dependent DNA ligase (Rv3014c) from M. tuberculosis: Strategies for inhibitor designBDB
Central Drug Research Institute
 
Design and synthesis of new 2-aryl, 3-benzyl- (1,3-oxazolidine or 1,3-thiazolidine)-4-ones as selective cyclooxygenase (COX-2) inhibitorBDB
Shahid Beheshti University