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59 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action.EBI
Universit£
Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity.EBI
Istituto Chimico Internazionale Dr. G. Rende
N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure.EBI
TBA
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.EBI
Universit£
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.EBI
Griffith University
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.EBI
Vilnius University
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,ß-glucuronidase inhibition activity, crystal structure, and POM analyses.EBI
King Saud University
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.EBI
Griffith University
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.EBI
Universidad Nacional De La Plata
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.EBI
Universit£
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.EBI
Universit£
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.EBI
Universit£
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.EBI
University Of Florida
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.EBI
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.EBI
Universit£
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.EBI
Universita Degli Studi Di Firenze
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.EBI
Universit£
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.EBI
Universit£
Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives.EBI
Griffith University
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.EBI
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrases as targets for medicinal chemistry.EBI
Universit£
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.EBI
Universit£
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.EBI
Kochi Medical School
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.EBI
Universit£
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.EBI
Universit£
(R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases.EBI
Universit£
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.EBI
Universita Degli Studi Di Firenze
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.EBI
University Of Tampere And Tampere University Hospital
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.EBI
Institute Of Biomedical Chemistry
Developments of small molecules as inhibitors for carbonic anhydrase isoforms.EBI
Georgia State University
Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer.EBI
University Of Florida
Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors.EBI
Universit£
Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors.EBI
Universit£
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy.EBI
University Of Florence
Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.EBI
University Of Florence
Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.EBI
Vilnius University
Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases.EBI
Kaunas University Of Technology
Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase.EBI
Merck Research Laboratories
Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition.EBI
Universit£
Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity.EBI
Department Of University Of Florence
Famotidine, an Antiulcer Agent, Strongly Inhibits EBI
University Of Florence
Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors.EBI
Vilnius University
Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases.EBI
Vilnius University
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology.EBI
University Of Florence
Bortezomib inhibits mammalian carbonic anhydrases.EBI
Universit£
Identification of a novel human eicosanoid receptor coupled to G(i/o).BDB
Tanabe Seiyaku
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.BDB
Smithkline Beecham Pharmaceuticals
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.BDB
Duke University
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist.BDB
Tokushima Research Institute
Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein.BDB
Albany Medical College
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.BDB
Abbott Laboratories
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells.BDB
University Of Arizona
Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes.BDB
Astellas Pharma
Discovery of 1-[9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride (CP-945,598), a novel, potent, and selective cannabinoid type 1 receptor antagonist.BDB
Pfizer