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19 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design.EBI
Technical University Of Dortmund
Irreversible protein kinase inhibitors: balancing the benefits and risks.EBI
Covalution Pharma
The selectivity of protein kinase inhibitors: a further update.EBI
University Of Dundee
7-Pyrrolidinyl- and 7-piperidinyl-5-aryl-pyrrolo[2,3-d]pyrimidines--potent inhibitors of the tyrosine kinase c-Src.EBI
Novartis Pharma Research
7-Alkyl- and 7-cycloalkyl-5-aryl-pyrrolo[2,3-d]pyrimidines--potent inhibitors of the tyrosine kinase c-Src.EBI
Novartis Pharma Research
Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.EBI
University Of Washington
SAR of 4-hydroxypiperidine and hydroxyalkyl substituted heterocycles as novel p38 map kinase inhibitors.EBI
Novartis Pharma
Substituted 5,7-diphenyl-pyrrolo[2,3d]pyrimidines: potent inhibitors of the tyrosine kinase c-Src.EBI
Novartis Pharma
Chemical Space of DNA-Encoded Libraries.EBI
University Of Utah
Development of a binding model to protein tyrosine kinases for substituted pyrido[2,3-d]pyrimidine inhibitors.EBI
Warner-Lambert
Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines.BDB
Harvard University
Cloning and functional expression of the human histamine H3 receptor.BDB
R. W. Johnson Pharmaceutical Research Institute
Venlafaxine: discrepancy between in vivo 5-HT and NE reuptake blockade and affinity for reuptake sites.BDB
Mcgill University
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.BDB
University Of California San Francisco