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28 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Decoys for docking.EBI
University Of California San Francisco
Identification and prediction of promiscuous aggregating inhibitors among known drugs.EBI
Northwestern University
A specific mechanism of nonspecific inhibition.EBI
Northwestern University
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening.EBI
Northwestern University
Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases.EBI
F. Hoffmann-La Roche
Design and synthesis of bridged gamma-lactams as analogues of beta-lactam antibiotics.EBI
Aventis Pharma
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.EBI
Basilea Pharmaceutica International
Deconstructing fragment-based inhibitor discovery.EBI
TBA
A high-throughput screen for aggregation-based inhibition in a large compound library.EBI
University Of California San Francisco
Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase.EBI
Università
Mechanism of inactivation of beta-lactamases by novel 6-methylidene penems elucidated using electrospray ionization mass spectrometry.EBI
Wyeth Research
Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases.EBI
Southern Methodist University
Structure-based approach for binding site identification on AmpC beta-lactamase.EBI
Northwestern University
Cephalosporin-derived inhibitors of beta-lactamase. Part 4: The C3 substituent.EBI
Southern Methodist University
Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors.EBI
Wyeth-Ayerst Research
Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.EBI
Merck Research Laboratorie
6-(1-Hydroxyalkyl))penam sulfone derivatives as inhibitors of class A and class C beta-lactamases II.EBI
Wyeth-Ayerst Research
6-(1-Hydroxyalkyl)penam sulfone derivatives as inhibitors of class A and class C beta-lactamases I.EBI
Wyeth-Ayerst Research
Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase.EBI
Northwestern University Medical School
Structure-based design of beta-lactamase inhibitors. 1. Synthesis and evaluation of bridged monobactams.EBI
F. Hoffmann-La Roche
Boronic acid inhibitors of the class A?-lactamase KPC-2.EBI
Ucl School Of Pharmacy
Selective indole-based ECE inhibitors: synthesis and pharmacological evaluation.BDB
Bayer Healthcare
A natural product ligand of the oxysterol receptor, liver X receptor.BDB
Eli Lilly