28 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Northwestern University
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening.
Northwestern University
Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases.
F. Hoffmann-La Roche
Design and synthesis of bridged gamma-lactams as analogues of beta-lactam antibiotics.
Aventis Pharma
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.
Basilea Pharmaceutica International
A high-throughput screen for aggregation-based inhibition in a large compound library.
University Of California San Francisco
Mechanism of inactivation of beta-lactamases by novel 6-methylidene penems elucidated using electrospray ionization mass spectrometry.
Wyeth Research
Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases.
Southern Methodist University
Structure-based approach for binding site identification on AmpC beta-lactamase.
Northwestern University
Cephalosporin-derived inhibitors of beta-lactamase. Part 4: The C3 substituent.
Southern Methodist University
Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors.
Wyeth-Ayerst Research
Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.
Merck Research Laboratorie
6-(1-Hydroxyalkyl))penam sulfone derivatives as inhibitors of class A and class C beta-lactamases II.
Wyeth-Ayerst Research
6-(1-Hydroxyalkyl)penam sulfone derivatives as inhibitors of class A and class C beta-lactamases I.
Wyeth-Ayerst Research
Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase.
Northwestern University Medical School
Structure-based design of beta-lactamase inhibitors. 1. Synthesis and evaluation of bridged monobactams.
F. Hoffmann-La Roche
Selective indole-based ECE inhibitors: synthesis and pharmacological evaluation.
Bayer Healthcare