PMID

Data

Article Title

Organization

Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold.

Slovak Academy Of Sciences

Targeting aldose reductase for the treatment of diabetes complications and inflammatory diseases: new insights and future directions.

Universit£

Synthesis and structure-activity relationship of 2-phenyliminochromene derivatives as inhibitors for aldo-keto reductase (AKR) 1B10.

Gifu Pharmaceutical University

Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.

Gifu Pharmaceutical University

Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17ß-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships.

University Of Pennsylvania

Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.

Universitat Aut£Noma De Barcelona

Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-ß-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1.

University Of Toyama

Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10.

Gifu Pharmaceutical University

Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.

Gifu Pharmaceutical University

Overview of AKR1C3: Inhibitor Achievements and Disease Insights.

China Pharmaceutical University

Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay.

Kyushu University

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity.

Comenius University In Bratislava

Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.

University Of Hradec Kralove

Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity.

Slovak Academy Of Sciences

Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase.

Universitat Aut£Noma De Barcelona

Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Gifu Pharmaceutical University