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12 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Dihydropyrimidine calcium channel blockers. 2. 3-substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.EBI
Squibb Institute For Medical Research
Dimeric 1,4-dihydropyridines as calcium channel antagonists.EBI
State University Of New York
Crystal structures and pharmacologic activities of 1,4-dihydropyridine calcium channel antagonists of the isobutyl methyl 2,6-dimethyl-4-(substituted phenyl)-1,4-dihydropyridine-3,5-dicarboxylate (nisoldipine) series.EBI
University Of Oslo
Optimization of ADME Properties for Sulfonamides Leading to the Discovery of a T-Type Calcium Channel Blocker, ABT-639.EBI
Abbvie
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.EBI
University Of Oxford
From hit to lead. Analyzing structure-profile relationships.EBI
Universities Of Lille
 
Phenyl-glycinol based NK1 receptor antagonists — towards the minimum pharmacophoreEBI
TBA
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine HEBI
Universit£
The discovery and optimization of benzimidazoles as selective NaEBI
Pfizer
MICE models: superior to the HERG model in predicting Torsade de Pointes.EBI
Chantest
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties.EBI
Emory University
4-Isoxazolyl-1,4-dihydropyridines: biological, theoretical, and structural studies.EBI
State University Of New York