PMID

Data

Article Title

Organization

Discovery of (3-(4-(2-Oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone (AZD1979), a Melanin Concentrating Hormone Receptor 1 (MCHr1) Antagonist with Favorable Physicochemical Properties.

Astrazeneca

Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition.

Amgen

Discovery of novel diarylketoxime derivatives as selective and orally active melanin-concentrating hormone 1 receptor antagonists.

Tsukuba Research Institute

Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2.

Amgen

Optimization of 2-piperidin-4-yl-acetamides as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Designing out hERG inhibition.

Astrazeneca R & D M£Lndal

Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R).

Tsukuba Research Institute

Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.

Tsukuba Research Institute

Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists.

Cerep

Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines.

Abbott Laboratories

Quinazoline and benzimidazole MCH-1R antagonists.

Argenta Discovery

4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.

Merck Research Laboratories

Synthesis and structure-activity relationships of piperidine-based melanin-concentrating hormone receptor 1 antagonists.

Schering-Plough Research Institute

Biaryl diamides as potent melanin concentrating hormone receptor 1 antagonists.

Schering-Plough Research Institute

6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.

7Tm Pharma

Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.

Schering-Plough Research Institute

4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists.

7Tm Pharma

A Novel Inhibitor of the Obesity-Related Protein FTO.

Basic Medical College Of Zhengzhou University