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39 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

Article Title
Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors.EBI
Academia Sinica
Virtual screening identification of novel severe acute respiratory syndrome 3C-like protease inhibitors and in vitro confirmation.EBI
Chonnam National University
Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives.EBI
Konkuk University
Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase.EBI
Konkuk University
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings.EBI
University of Illinois At Chicago
Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors.EBI
Tianjin University of Science and Technology
Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors.EBI
Kansas State University
Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.EBI
Korea Research Institute of Bioscience and Biotechnology
Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases.EBI
The Chinese University of Hong Kong
Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.EBI
Academia Sinica
Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition.EBI
Korea Research Institute of Bioscience and Biotechnology
SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii.EBI
Korea Research Institute of Bioscience and Biotechnology
Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.EBI
National Human Genome Research Institute
New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors.EBI
Kyoto Pharmaceutical University
Novel small-molecule inhibitors of transmissible gastroenteritis virus.EBI
National Health Research Institute
Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors.EBI
Purdue University
Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element.EBI
Wichita State University
A selective matrix metalloprotease 12 inhibitor for potential treatment of chronic obstructive pulmonary disease (COPD): discovery of (S)-2-(8-(methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408).BDB
Wyeth Research
Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.BDB
Boehringer Ingelheim Pharmaceuticals
Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors.BDB
Universita Di Pisa
Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors.BDB
Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors.BDB
University of Alberta