The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

27 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.EBI
University of Kentucky
Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.EBI
University of Arkansas For Medical Sciences
Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.EBI
University of Kentucky
Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake.EBI
University of Kentucky
Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2).EBI
University of Arkansas For Medical Sciences
Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.EBI
University of Kentucky
Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2).EBI
University of Kentucky
Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.EBI
University of Kentucky
Synthesis and biological evaluation of 3-alkyl-dihydrotetrabenazine derivatives as vesicular monoamine transporter-2 (VMAT2) ligands.EBI
University of Pennsylvania
Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors.EBI
China Pharmaceutical University
Quinlobelane: a water-soluble lobelane analogue and inhibitor of VMAT2.EBI
University of Kentucky
Synthesis and evaluation of 2-amino-dihydrotetrabenzine derivatives as probes for imaging vesicular monoamine transporter-2.EBI
Key Laboratory of Radiopharmaceuticals (Beijing Normal University)
Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2.EBI
University of Kentucky
Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.EBI
University of Kentucky
Ibogaine and Their Analogs as Therapeutics for Neurological and Psychiatric Disorders.EBI
Usona Institute
Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands.EBI
University of Kentucky
Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors.EBI
Yantai University
Biotransformation: Impact and Application of Metabolism in Drug Discovery.EBI
Hypha Discovery
Synthesis and in vitro evaluation of water-soluble 1,4-diphenethylpiperazine analogs as novel inhibitors of the vesicular monoamine transporter-2.EBI
University of Kentucky
The Druggability of Solute Carriers.EBI
The Scripps Research Institute
In vitro and in vivo studies of benzisoquinoline ligands for the brain synaptic vesicle monoamine transporter.EBI
University of Michigan Medical School
Exploring the effect of EBI
University of Arkansas For Medical Sciences
Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [EBI
University of Kentucky
OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERSBDB
Columbia University
OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERSBDB
Columbia University
[9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11BH-pyrido-[2,1-a]isoquinolin-2-yl]methanol and compounds, compositions and methods relating theretoBDB
Neurocrine Biosciences
Identification of conformationally sensitive residues essential for inhibition of vesicular monoamine transport by the noncompetitive inhibitor tetrabenazine.BDB
Hebrew University of Jerusalem