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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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50 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Therapeutically active compounds and their methods of useBDB
Servier Pharmaceuticals
INHIBITORS OF MUTANT IDH1 AND IDH2BDB
University Of Texas
Therapeutically active compounds and their methods of useBDB
Servier Pharmaceuticals
7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitorsBDB
Eli Lilly
7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitorsBDB
Eli Lilly
Inhibiting mutant IDH-1BDB
Forma Therapeutics
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH1)BDB
Forma Therapeutics
Inhibiting mutant IDH-1BDB
Forma Therapeutics
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1)BDB
Forma Therapeutics
Iridinesulfonamide compound and use method thereofBDB
Chia Tai Tianqing Pharmaceutical Group
Sultam compound and application method thereofBDB
Chai Tai Tianqing Pharmaceutical Group
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitorsBDB
Eli Lilly
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
Fused imidazoles as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Fused amino pyridine as HSP90 inhibitorsBDB
Curis
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
Mutant IDH1 inhibitorsBDB
Eli Lilly
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
Therapeutically active compositions and their methods of useBDB
Agios Pharmaceuticals
Methods and compositions for cell-proliferation-related disordersBDB
Agios Pharmaceuticals
Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitorsBDB
Forma Therapeutics
Tricyclic compounds as inhibitors of mutant IDH enzymesBDB
Merck Sharp & Dohme
Tricyclic compounds as inhibitors of mutant IDH enzymesBDB
Merck Sharp & Dohme
Benzimidazol-2-amines as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
5-hydroxyalkylbenzimidazoles as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Tricyclic compounds as inhibitors of mutant IDH enzymesBDB
Merck Sharp & Dohme
N-Methylbenzimidazoles as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Inhibitor of the mutated isocitrate dehydrogenase IDH1 R132HBDB
Bayer Pharma Aktiengesellschaft
Benzimidazol-2-amines as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Benzimidazol-2-amines as MIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitorsBDB
Forma Tm2
Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereofBDB
Sunshine Lake Pharma
Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitorsBDB
Forma Tm2
Therapeutically active compositions and their methods of useBDB
Agios Pharmaceuticals
Therapeutic compounds and compositionsBDB
Agios Pharmaceuticals
Phenyl and pyridinyl substituted piperidines and piperazines as inhibitors of IDH1 mutants and their use in treating cancerBDB
Agios Pharmaceuticals
2-aryl- and 2-arylalkyl-benzimidazoles as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitorsBDB
Forma Therapeutics
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
Benzimidazol-2-amines as MIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumorsBDB
Bayer Pharma Aktiengesellschaft
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDHBDB
Novartis
Tricyclic compounds as inhibitors of mutant IDH enzymesBDB
Merck Sharp & Dohme
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
Heterocyclic derivatives and their use in the treatment of neurological disordersBDB
Novartis
Isoxazole derivative as mutant isocitrate dehydrogenase 1 inhibitorBDB
Daiichi Sankyo
Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.BDB
National Institutes of Health
New IDH1 mutant inhibitors for treatment of acute myeloid leukemiaBDB
Albert Einstein College of Medicine
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDHBDB
Novartis