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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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12 articles for H Sham


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors.EBI
Global Blood Therapeutics
Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.EBI
Abbott Laboratories
Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.EBI
Abbott Laboratories
Synthesis and biological evaluation of 4-[(3-methyl-3H-imidazol-4-yl)-(2-phenylethynyl-benzyloxy)-methyl]-benzonitrile as novel farnesyltransferase inhibitor.EBI
Abbott Laboratories
Synthesis and biological evaluation of 4-[3-biphenyl-2-yl-1-hydroxy-1-(3-methyl-3H-imidazol-4-yl)-prop-2-ynyl]-1-yl-benzonitrile as novel farnesyltransferase inhibitor.EBI
Abbott Laboratories
Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores.EBI
Abbott Laboratories
Discovery of a series of cyclohexylethylamine-containing protein farnesyltransferase inhibitors exhibiting potent cellular activity.EBI
Abbott Laboratories
Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy.EBI
Abbott Laboratories
Potent and orally bioavailable noncysteine-containing inhibitors of protein farnesyltransferase.EBI
Abbott Laboratories
Potent inhibitors of protein farnesyltransferase: heteroarenes as cysteine replacements.EBI
Abbott Laboratories
Fragment ligated inhibitors selective for the polo box domain of PLK1BDB
University of South Carolina
Hydroxyethylene sulfones as a new scaffold to address aspartic proteases: design, synthesis, and structural characterization.BDB
Philipps-Universitat Marburg