The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Disulfiram derivatives as ALDH1A1 and MAGL inhibitorsBDB
Batterjee Medical College
Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitorsBDB
Pfizer
Pyridylamino substituted heterotricyclic compounds, and preparation method and pharmaceutical use thereofBDB
TBA
Pyrazolo[1,5-a]pyrazin-4-yl derivativesBDB
Pfizer
Piperidine derivatives as inhibitors of ubiquitin specific protease 7BDB
Almac Discovery
Heterocyclylamines as PI3K inhibitorsBDB
Incyte
Heteroaromatic compounds as BTK inhibitorsBDB
Boehringer Ingelheim International
Isoxazole derivatives as FXR agonists and methods of use therofBDB
Enanta Pharmaceuticals
Heterocyclic compounds as PI3K-γ inhibitorsBDB
Incyte
Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis.BDB
University of Pavia
Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity.BDB
Roche Products
 
Ring Size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol.BDB
Sphinx Laboratories
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.BDB
Academy of Sciences of The Czech Republic
In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.BDB
National Cancer Institute-Bethesda
Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors.BDB
Upjohn
Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors.BDB
Upjohn
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.BDB
Merck Research Laboratories
L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor.BDB
Merck Research Laboratories
Structure-activity relationship of small-sized HIV protease inhibitors containing allophenylnorstatine.BDB
Japan Energy
Understanding binding affinity: a combined isothermal titration calorimetry/molecular dynamics study of the binding of a series of hydrophobically modified benzamidinium chloride inhibitors to trypsin.BDB
University of Groningen