BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 772K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

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12 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
7
Berkeleyones and related meroterpenes from a deep water acid mine waste fungus that inhibit the production of interleukin 1-ß from induced inflammasomes.EBI
The University of Montana
56
Interleukin-1β converting enzyme (ICE): A comprehensive review on discovery and development of caspase-1 inhibitors.EBI
L J University Ahmedabad
10
Fragment-to-Lead Medicinal Chemistry Publications in 2022.EBI
Astex Pharmaceuticals
13
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches.EBI
Novartis
27
Human disorders associated with inflammation and the evolving role of natural products to overcome.EBI
University of Delhi
25
Substituted sulfonylurea derivativesBDB
Zydus Lifesciences
117
NLRP3 inflammasome inhibitorsBDB
Novartis
196
Indole derivatives and their use in neurodegenerative diseasesBDB
Merck Patent
196
Indole derivatives and their use in neurodegenerative diseasesBDB
Merck Patent
1
Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke.BDB
Taisho Pharmaceutical
10
Methods for the treatment of locally advanced breast cancerBDB
Celgene
0
 
Inhibiting protein-protein interactions: a model for antagonist designBDB
Pfizer