70 articles for YS Lee
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects.
Seoul National University
Identification of novel estrogen receptor (ER) agonists that have additional and complementary anti-cancer activities via ER-independent mechanism.
Kyung Hee University
Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.
Korea Institute of Science and Technology
Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors.
Kyung Hee University
Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor.
University of Arizona
Discovery of 4-aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 inhibitors. Part I: optimization of in vitro potencies and pharmacokinetic properties.
Development Center For Biotechnology
Synthesis of aminoalkyl-substituted coumarin derivatives as acetylcholinesterase inhibitors.
Kyung Hee University
Synthesis, characterization and Akt phosphorylation inhibitory activity of cyclopentanecarboxylate-substituted alkylphosphocholines.
Kyung Hee University
Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease.
Korea Institute of Science and Technology
Discovery of potent and selective rhodanine type IKKß inhibitors by hit-to-lead strategy.
Korea University
Design and synthesis of trivalent ligands targeting opioid, cholecystokinin, and melanocortin receptors for the treatment of pain.
University of Arizona
Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives.
Kyung Hee University
Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.
Shenyang Pharmaceutical University
Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.
University of Arizona
Synthesis and biological activity of 3,4-dihydroquinazolines for selective T-type Ca2+ channel blockers.
Korea Institute of Science & Technology
A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5.
Korea Institute of Science & Technology
Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides.
Institute of Science and Technology
Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selectiveµ-antagonist activity.
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholism
Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers.
Korea Institute of Science and Technology
Synthesis of cinnamoyl ketoamides as hybrid structures of antioxidants and calpain inhibitors.
College of Pharmacy Kyung Hee University
Probes for narcotic receptor mediated phenomena. 41. Unusual inverseµ-agonists and potentµ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans.
National Institute On Drug Abuse
Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate.
Harvard University
Discovery of pyrrole-indoline-2-ones as Aurora kinase inhibitors with a different inhibition profile.
Development Center For Biotechnology
Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols.
Nida
Probes for narcotic receptor mediated phenomena. 39. Enantiomeric N-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans.
National Institute On Drug Abuse and The National Institute On Alcohol Abuse and Alcoholi
Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers.
National Institute On Drug Abuse
Synthesis of tyrosinase inhibitory (4-oxo-4H-pyran-2-yl)acrylic acid ester derivatives.
Institute of Science and Technology
Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers.
Institute of Science and Technology
Synthesis and biological evaluation of O4'-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents.
Mansoura University
Design and synthesis of 4-quinolinone 2-carboxamides as calpain inhibitors.
Kyung Hee University
Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta.
Crystalgenomics
Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series.
National Institute On Drug Abuse
Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis.
Ewha Womans University
Cannabinoformins: Designing Biguanide-Embedded, Orally Available, Peripherally Selective Cannabinoid-1 Receptor Antagonists for Metabolic Syndrome Disorders.
National Institute On Alcohol Abuse and Alcoholism (NIAAA)
Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors.
University of Arizona
Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors.
University of Arizona
Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.
University of Arizona
Pharmacophore-based virtual screening: the discovery of novel methionyl-tRNA synthetase inhibitors.
Seoul National University
Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents.
Seoul National University
Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.
Seoul National University
Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
Seoul National University
Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors.
Institute of Science & Technology
C-terminal modified Enkephalin-like tetrapeptides with enhanced affinities at the kappa opioid receptor and monoamine transporters.
University of The Punjab
Synthesis, Biological Evaluation, and Molecular Modeling Studies of 3,4-Diarylpyrazoline Series of Compounds as Potent, Nonbrain Penetrant Antagonists of Cannabinoid-1 (CB
National Institute On Alcohol Abuse and Alcoholism
Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs.
Seoul National University
3,4-Dihydroquinazoline derivatives as novel selective T-type Ca2+ channel blockers.
Institute of Science & Technology
Solid-phase synthesis of kojic acid-tripeptides and their tyrosinase inhibitory activity, storage stability, and toxicity.
Seoul National University
Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors.
Institute of Science & Technology
Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.
Korea Institute of Science & Technology (Kist)
Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers.
Korea University
6-Hydroxy-1,3-dioxin-4-ones as non-peptidic HIV protease inhibitors.
Institute of Science & Technology
A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model.
Korea Institute of Science & Technology (Kist)
Synthesis and dual biological effects of hydroxycinnamoyl phenylalanyl/prolyl hydroxamic acid derivatives as tyrosinase inhibitor and antioxidant.
Seoul National University
Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid.
Korea Institute of Science and Technology
Vanillic acid glycoside and quinic acid derivatives from Gardeniae Fructus.
Korea Institute of Science and Technology
Caffeoylglycolic and caffeoylamino acid derivatives, halfmers of L-chicoric acid, as new HIV-1 integrase inhibitors.
Korea Institute of Science & Technology
Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.
Yonsei University
Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB
Kyung Hee University
Cyclic biphalin analogues with a novel linker lead to potent agonist activities at mu, delta, and kappa opioid receptors.
University of Arizona
Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.
National Institute On Drug Abuse and The National Institute On Alcohol Abuse
