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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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20 articles for PC Tyler


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Tight binding enantiomers of pre-clinical drug candidates.EBI
Victoria University of Wellington
Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.EBI
Industrial Research
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.EBI
Industrial Research
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.EBI
Industrial Research
Immucillins in custom catalytic-site cavities.EBI
Albert Einstein College of Medicine of Yeshiva University
Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.EBI
Industrial Research
Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.EBI
Industrial Research
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.EBI
Industrial Research
Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.EBI
Industrial Research
Design and synthesis of potent"sulfur-free" transition state analogue inhibitors of 5'-methylthioadenosine nucleosidase and 5'-methylthioadenosine phosphorylase.EBI
Industrial Research
8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.EBI
Industrial Research
Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase.EBI
Albert Einstein College of Medicine
CRBN ligands and uses thereofBDB
Kymera Therapeutics
Buprenophine analogsBDB
Purdue Pharma
Substituted 1,4-benzodiazepine-2,5-diones as alpha-helix mimetic antagonists of the HDM2-p53 protein-protein interaction.BDB
Johnson & Johnson Pharmaceutical Research & Development
Structural requirements for factor Xa inhibition by 3-oxybenzamides with neutral P1 substituents: combining X-ray crystallography, 3D-QSAR, and tailored scoring functions.BDB
Aventis Pharma Deutschland
Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents.BDB
Glaxosmithkline