26 articles for JE Bradner
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.
Colorado State University
Biased multicomponent reactions to develop novel bromodomain inhibitors.
Dana-Farber Institute
Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs.
Colorado State University
A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold.
Broad Institute of Harvard and Mit
Discovery of histone deacetylase 8 selective inhibitors.
Howard Hughes Medical Institute
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib.
Harvard Medical School
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
University of Toronto
Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold.
Dana Farber Cancer Institute
Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors.
University of Massachusetts-Boston
BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.
University of Minnesota
Composition for suppressing neuraminidase activity comprising geranylated flavonoid derived from Paulownia tomentosa as active ingredient
Industry-Academic Cooperation Foundation Gyeongsang National University
Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents
Bayer Pharma Aktiengesellschaft
INTERACTION OF AROMATIC COMPOUNDS WITH ALPHA-CHYMOTRYPSIN. II. COMBINATION OF THE ISOMERIC INDOLE CARBOXAMIDES AND CARBOXYLATE IONS WITH THE ACTIVE SITE.
California Institute of Technology
MASPIT: three-hybrid trap for quantitative proteome fingerprinting of small molecule-protein interactions in mammalian cells.
Gpc Biotech