15 articles for F Kozielski
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Depsidones from Lichens as Natural Product Inhibitors of M-Phase Phosphoprotein 1, a Human Kinesin Required for Cytokinesis.
University College London
New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.
Cnrs
Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism.
The Beatson Institute For Cancer Research
Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models.
The Beatson Institute For Cancer Research
Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.
University of Strathclyde
Receptor-ligand interaction-based virtual screening for novel Eg5/kinesin spindle protein inhibitors.
Korea Institute of Science and Technology
Triphenylbutanamines: kinesin spindle protein inhibitors with in vivo antitumor activity.
The Beatson Institute For Cancer Research
Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5.
Institute For Cancer Research
Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol.
Institute For Cancer Research
Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration.
Cnrs-Commissariat à
Phenyl Bis-Sulfonamide Keap1-Nrf2 Protein-Protein Interaction Inhibitors with an Alternative Binding Mode.
University College London
Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.
University College London
Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5.
University of Kwazulu-Natal (Ukzn)
