BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for JR Thomason

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition.EBI
Pfizer
3,4-Disubstituted benzofuran P1' MMP-13 inhibitors: optimization of selectivity and reduction of protein binding.EBI
Wyeth Research
Inhibition of Tpl2 kinase and TNFalpha production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis.EBI
Wyeth Research
Inhibition of Tpl2 kinase and TNF-alpha production with 1,7-naphthyridine-3-carbonitriles: synthesis and structure-activity relationships.EBI
Wyeth Research
Synthesis and SAR of highly selective MMP-13 inhibitors.EBI
Wyeth Research
Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11.EBI
Forma Therapeutics
Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.EBI
Pfizer
Cyano cyclobutyl compounds for CBL-B inhibition and uses thereofBDB
Nurix Therapeutics
Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitorsBDB
Fedora Pharmaceuticals
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.BDB
Fred Hutchinson Cancer Research Center
Somatostatin receptor subtype 4 (SSTR4) agonistsBDB
Centrexion Therapeutics