The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for ML Boys


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring.EBI
Pfizer
Discovery of 5-Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors.EBI
Pfizer
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists.EBI
Pfizer
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties.EBI
Pfizer
Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonists.EBI
Pfizer
5-Alkyl-2-urea-Substituted Pyridines: Identification of Efficacious Glucokinase Activators with Improved Properties.EBI
Amgen
Pyrazine derivative and application thereof in inhibiting SHP2BDB
Suzhou Genhouse Pharmaceutical
Dipeptidyl ketoamide meta-methoxyphenyl derivatives and uses thereofBDB
Landsteiner Genmed
Cyclic dinucleotides as sting agonistsBDB
Janssen Biotech
Benzimidazole derivatives as EP4 ligandsBDB
Bayer Pharma Aktiengesellschaft
Small-molecule HSP90 inhibitorsBDB
Memorial Sloan-Kettering Cancer Center
2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infectionsBDB
Gilead Pharmasset
Pyridinones/pyrazinones, method of making, and method of use thereofBDB
Genentech
Diversity-oriented fluorescence library approach (DOFLA) to the discovery of chymotrypsin sensor.BDB
New York University
Thiazole derivatives as inhibitors of purified bovine liver mitochondrial monoamine oxidase-B: structure-activity relationships and theoretical study.BDB
University of Catania
A structure-guided approach to creating covalent FGFR inhibitors.BDB
Harvard Medical School