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13 articles for M Lewis


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
The discovery of potent agonists for GPR88, an orphan GPCR, for the potential treatment of CNS disorders.EBI
Lexicon Pharmaceuticals
Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.EBI
Bristol-Myers Squibb
Novel interactions of fluorinated nucleotide derivatives targeting orotidine 5'-monophosphate decarboxylase.EBI
University Health Network
Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans.EBI
Pfizer
Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability.EBI
Pfizer
Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors.EBI
Bristol Myers Squibb
SAGE-718: A First-in-Class EBI
Sage Therapeutics
Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.EBI
Bristol Myers Squibb
Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents.EBI
Serenex
Substituted heteroaryls as inhibitors of the BCL6 BTB domain protein-protein interactionBDB
Ontario Institute For Cancer Research (Oicr)
Azaspirocycles as monoacylglycerol lipase modulatorsBDB
Janssen Pharmaceutica
COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORSBDB
Nuevolution
Ligand structure-activity requirements and phospholipid dependence for the binding of phorbol esters to protein kinase D.BDB
University of Pittsburgh